Biophotonics & Microsystems Laboratory

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MEMS Based Optical Coherence Tomography

Shuguang Guo

Sponsor(s): NSF

Introduction to OCT

OCT is analogous to ultrasound imaging which relies on measuring the time-of-flight of reflected echoes.  However, because the speed to light is orders of magnitude faster than sound, OCT uses low coherence interferometry rather than reflection time measurement to measure the light reflection positions thus to obtain cross sectional images of the sample.

Time domain OCT sytem

 

 

 

 

Why OCT?

  •    Noncontact (unlike ultrasound)

  •    Noninvasive, non-ionizing (unlike X-rays)

  •    High contrast with molecular signature

  •    High spatial resolution

  •    Inexpensive, portable

Objectives

         Build up a time domain OCT system and a Fourier domain OCT system

         Use innovative MEMS technology to manufacture miniature endoscopic and intravascular probes

         Enable noninvasive or minimally invasive, real-time, 3-D, in vivo OCT imaging

Applications:

          Endoscopic subsurface imaging of tissues

          Detection of early stage cancer

          Guidance of surgery

MEMS BASED PROBES

 

PRELIMINARY RESULTS

 

 

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Biophotonics & Microsystems Lab, 136 Larsen Hall, PO Box 116200, Gainesville, FL 32611-6200.

Phone : (352) 392-1049         Fax : (352) 846-1416

 
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