BML project

Biophotonics & Microsystems Laboratory

2D MEMS mirror based in-vivo endoscopic imaging probe

Students: Lei Wu
Advisor: Huikai Xie, University of Florida, Min Gu, Swineburne University of Technology (MGu [at] groupwise.swin.edu.au)
Sponsor(s): NSF, Florida Photonics Center of Excellence, Australia Research Council

Objectives

• Develop MEMS micromirror scanner that can perform center-fixed 2D scanning

• Integration of MEMS mirror into miniaturized endoscopic imaging (OCT and Two-photon) probe for in-vivo imaging at cellular level early cancer detection.

Technical Approach

• Double clad fiber based two-photon imaging system

• Surface and bulk-combined micromachining batch process for 2D MEMS mirror

Accomplishment

• Demonstrated the 1st generation probe (5mm diameter) and two-photon excited fluorescence (TPEF) imaging with 5mm resolution has been obtained.

• Demonstrated center-fixed 2D scanning micromirror with large optical angles (~±50º) at low driving voltage (<10V) and the 2nd generation probe based on the new mirror.

Applications:

• Real-time In-vivo biomedical (OCT, 2-photon) endoscopic imaging


	Scanning motion of the MEMS mirror in the probe


	2D scanning pattern of the probe (without GRIN lens)

Publications

• L. Wu, L. Fu, A. Jain, T. Nishida, M. Gu, and H. Xie, IEEE/LEOS Annual Meeting, Lake Buena Vista, FL, Oct. 2007.